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Meaning in Life in Palliative Cancer Care: Psychosocial and Existential Outcomes—A Systematic Review

Background: Existential distress, marked by hopelessness, loss of meaning, and spiritual suffering, is prevalent among patients with advanced illness, and is associated with psychological burden…

By Francisco Rodrigues-Fouto, Paulo Reis-Pina

Published: Feb 2026

Non-verbal methods for assessing grief and mental health in children and individuals with additional communication needs: A scoping review

Introduction:Bereavement affects individuals in diverse ways, and the support they require can vary significantly. For grief to be effectively recognised and addressed in both clinical and research…

By Noreen Hopewell-Kelly, Silvia Goss, Mala Mann, Linda Machin, Timothy Pickles, Freya Field, Letizia Perna, Lucy Selman, Emily Harrop

Published: Feb 2026

Psilocybin-assisted psychotherapy for psycho-existential distress in advanced cancer: a narrative review

Introduction: This article presents a narrative review of psilocybin-assisted psychotherapy as a promising intervention for addressing anxiety, depression and psycho-existential distress in patients…

By Luca Magnani, Luca Ghirotto, Fabio Fesce, Tania Re, Silvia Tanzi, Andrea Amerio, Alessandra Costanza

Published: Feb 2026

Needs and health-related quality of life domains relevant to people in Europe with advanced cancer in need of palliative care: a systematic review of qualitative research

Purpose:There is a need for a comprehensive summary of qualitative research on the health-related quality of life (HRQoL) of people with advanced cancer requiring palliative care. We aim to…

By Catalina Lizano-Barrantes, Clara Amat-Fernandez, Olatz Garin, Ricardo Luer-Aguila, Yolanda Pardo, Leslye Rojas-Concha, Melissa S.Y. Thong, Giovanni Apolone, Cinzia Brunelli, Augusto Caraceni, Norbert Couespel, Nanne Bos, Mogens Groenvold, Stein Kaasa, Gennaro Ciliberto, Claudio Lombardo, Ricardo Pietrobon, Gabriella Pravettoni, Aude Sirven, Hugo Vachon, Alexandra Gilbert, Galina Velikova, Montse Ferrer, EUonQoL Working Group

Published: Feb 2026

Distinct trajectories of emotional distress and physical health among informal dementia caregivers surrounding bereavement: a systematic review

Background: Informal caregivers of individuals with dementia experience substantial psychological and physical burdens, with bereavement marking a critical transition. However, the longitudinal…

By Ji-Won Kim, Ji-Won Oh, Bo-Min Kim, Ji-Eun Choi, Chan-Young Kwon

Published: Feb 2026

Coping of informal caregivers for people with terminal illnesses: A systematic review and metasynthesis

Background:Informal caregivers are vital in providing end-of-life care to their loved ones. However, there is a lack of systematic understanding of their coping strategies during the caregiving…

By Ming Shin Leung, Yong Hao Ng

Published: Jan 2026

The Influence of Spirituality in the Care of Patients with Advanced Chronic Illnesses and at the End of Life: An Integrative Review

Spirituality is a central yet often overlooked component of care, particularly for people facing advanced chronic illness or approaching the end of life. This integrative review examined evidence on…

By José M. Pérez-Jiménez, Patricia Bonilla Sierra, Rocío de-Diego-Cordero

Published: Jan 2026

Life Review Interventions in Palliative Care: A Systematic Review of Patient-Centered Outcomes

Background: Life Review Interventions (LRI) are gaining attention in palliative care as a therapeutic approach to support psychological and spiritual needs. However, their effectiveness remains…

By Margarida Pascoal-Carvalho, Paulo Reis-Pina

Published: Jan 2026

Psilocybin-assisted therapy for individuals with palliative care needs: A systematic review of safety and efficacy

Background:Palliative Care is concerned with relieving suffering and improving the quality of life of patients and their families. Currently, questions arise about how to provide patients with good…

By Ana Rita Sousa Matos, Ana Catarina Silva, Licínio Rego, Rui Fernandes, Sara Gonçalves

Published: Dec 2025